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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2cf35ae0d923045cd9e83820c800857191f1436303c9260181f12cd3523d0d0d' 
  AND token = 'V5TJTvupf3Wtjb9/WjUJ6mdkvP+uqR4L9Io8Gd7i9Rw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}