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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a8718209d2ffe07995f8f9cc9012cff84578a95b5b297766c65051016f224429' 
  AND token = '+lxu8UFTbB93HnoL5eIfmzBD/Xkb+0QR4vpKL0S97o8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00044

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}