SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b31bd55f7dd3cbe0e4e145f60cfd2638147134d23556708ff66fa7e7c0881c0c' 
  AND token = 'LOQPDGO46RjK0DTkYbDKRv+ZPbFjt0HOF3wUl5moDwU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}