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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '02a84908b47cd0177e9ba85bc6d84d3013bb9cc6b19b70381b58a4e263ea5210' 
  AND token = 'mSSryo1UPvE/tNec650BWggLpyviFHfQzbnLfd5DiPw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}