SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b725faffccf88dc4e918b3629fa2a4c7a1d16eb4e72f3e78683ccead8fdf754d' 
  AND token = 'A5W7j9dxzEiZQaW4r2ui60PBe4djT3yxaheviUgiGAA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}