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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '67e6cef4dbf4a4d691da2067747499dac562a3c6fef7bbaa467ebcb80313d517' 
  AND token = '07txIhuCwhj9AYipdMRfrBq/tXhtwKzqXfhg+a70ljc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}