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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4d6ff24c10ece3f1c3bfc48ab4848cbc91e504fd3a2f7a48a4df1fde0d3eff8e' 
  AND token = 'xYHAXD/gVMyXsQx7TOdQ16njM/nB6nc+opj6lLdh8Lg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}