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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b0b42b04caf67c0804e03a67f694c56ce456e52bd2d7b876ccb4ea9fcbddafc2' 
  AND token = 'vadYWE+xA4NYKBJLC5LaEaT/QPLzrg+lApa2kkgEpCQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}