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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '682edf5bcdbd5e994a2e862f9b45708bc68818481392cd19be484d092a08009e' 
  AND token = 'yKL2K3Tsg7HREwhdZw+naT00Ctl0KyCcXRD946H//VM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}