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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cffd850f0304184d9fcdde67fa2e5a2a6a4bae484872c849c2a8ced10edfe86d' 
  AND token = 'vl8mks3VyMjNp1pVCQ3vnRfSJlDB3XaGcRxW+s0YLNM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00060

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}