SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '06a538b0aea4f468fa4b1bbca64b731e6c0a3a7797eef3fca5f294f464c5c71e' 
  AND token = 'QZWG3EabvcPoFzu4G20tS82exd06fl0Q1eg+utSoU5I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}