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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0354e0f150d52c53fecee6545d81ece5cf6fe1e8c516c2bc119bd81f8b6d4686' 
  AND token = 'ZyUUG4rT+2zpvHN1kbO9eZKa3NyFB9hV1+amn5VGjhU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}