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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8d1e9166da5b9a371f5b6e66d3feaedfda51ffe0c3ed05d5793471dfd6402e47' 
  AND token = 'PyU2VE0KCgJ+7wf+SLpCBC2VM2zS6x2JECdhNUrPHP4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00013

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}