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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd66479fcdf168c570aa24c9e43639e736214f839cb481f7ae12a6a4b680e23f7' 
  AND token = 'u0DiP7wvp4BGBLL2iSkXeeNr/YjjL4/G59CF7ygmXEA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}