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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '80e3c1d815502450bddf16a26c84fab92e773a4cdc7d4f8cd65ca82a9c5ce01b' 
  AND token = '9CsJQ/T68mRaIOfkq4wCAlGVrj9VvroPuhAsHxdCoos=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}