SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '57f1ccfb03e39f764da108d0700241a8ba3ea45888bb35ca4fe17b04d9f6c647' 
  AND token = 'CazjLiuEqWMrAKhdhlcUlRLJJpFLkAzA66JDBsJzL0g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}