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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '52c9055162b09b2826546f5fb3ab4cb348105b4302a802a5bb2bfc8d082174be' 
  AND token = 'VztGMDtKcb125OQHVVqtq2UtXe1C02YuryzZyirlHAk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00038

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}