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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5204c3d4b51b0a376762bdd807cc7a0e55e2fc2dc6cb7adbee2b05166e0d4443' 
  AND token = 'p91fLTVp/PIn+ZrQ0qy2RfjseEWbZ1c5l9Ca2r+nf3o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}