SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '79b86c455fcc9e47aa88cd95d772b7c5c289c8c21cb0a2aa474f090dac1e452e' 
  AND token = 'OgGy5LNmO/x0Unzm2slrmFZjNXs2RKxtWCtq9nqt+8k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00052

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}