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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e09b469cb0867b0a85d8a65cc21c1a63dd9d50a4fe994f83cd6577accd31cc49' 
  AND token = 'SXxUWGVjWXX7HOGFBYFtEQw+3BM5dQ3H1+cOXvuhNPU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}