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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f7278e8ea671eeb7b5c7ba179bd2a188e7090a16257f66ebee804f9ebda27eec' 
  AND token = '4mGLZgDFAZlTZZVIZcuNcFzVy8fZlNUId8285tU3A70=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}