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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a38390d44473308c26114b09f57deefddf546600e35f2fa723afc1ccf14f2127' 
  AND token = 'Cn4KqhgiiSWA8LT7U59f7im2F+l0jIkb5gFMWwOSRAc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}