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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '06491d99ed8f002a8c4a2a8c7a35ce45b3abf9dab292e20f42faad3b69bd7a93' 
  AND token = 'nGTD8A6bF1KZ2nsSDR+/j+SBuj0G26zqBFVUnDWN7IQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}