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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '43d581f496bbed8a9ec75ee405b88f979b201c5257cb764ca00ee54d5d4ed578' 
  AND token = 'jWwUV6BSjQLQ3Em50nXMYrQLPoRsX37Wc8DVjzDc22c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}