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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '32a6ed0264dba8b4b5bb18c74c3b7ee79d1728cf7211a5ef4d33327b4972c4f6' 
  AND token = 'EM9uEce6IxAYF0yq7P2+xbQcVVe/bA7A5IGdvVxbjXI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}