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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8cd4cae729f486240c71aaae0f6fad0e0defde01771d8dec84d63ac42df7f8f2' 
  AND token = 'OhRhFgX9dDmVkKm9PNPlsIhT6MB7Iotk8pv8AOqe7uI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}