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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6ff8cb5b3dfa9340081c4699a4c88b319edee58180d4a413cf8e6abf4fe453cb' 
  AND token = 'xX9dMCnc/u85D7A1bLiG5YS2A6T7xU7ekTbcMhz0kPI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}