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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'df1b4619cafe233fb570383ccdb18878b081d47a37bc4a20e0a4a846c4b72334' 
  AND token = 'FjppJ5E+8CdxwA3YgbAtbBotEsWXfR3/1DR49nvZVrc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}