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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '318477bb37a4aa29fa68fd25716057e0319bdec4a39ba7e3497a10317a4dc054' 
  AND token = 'sNwFYJeyzpoYoXYNS0hEkX1kO0yujsCj/3kxrRUMGDw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}