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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ca0b973d29666d23a5b0ee191cff3746387fb8072fe6d5765c8baa1fd3397a22' 
  AND token = 'zwAd/NTgQO5xywh3EdqUogFJQvO3LEmo7hKcgx3s4dE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00104

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}