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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '860a85a8e1649cdf129d44826e9c73c7bdb53303ce95167ccd5a19a1c76c3be1' 
  AND token = 'fIBNA++XfKy1KsUQGKix3Otp9esKTUMSlwRIZ38iBCI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00051

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}