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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e24ba1d4ec4f21a27509e16b470ae342ec0282b90b7589cfed0ae69ed7940b0e' 
  AND token = 'uLtaCUc5rRjeM0oYBCy7An5du2ojHJNY26ozuM6b1EM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}