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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1f7eb46d3989ad134c5168b567f0da72a892765a82739ba2754a9e4f226e31a5' 
  AND token = 'eaGv+8XR5z/b0gT+NhXGMIipRYZsk4056affGjvYl3k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}