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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c72adff2f8b4ba5aad8082f8a93cdd91f9a220cedd2c17d95627466613f2dd2a' 
  AND token = 'EpKthq0/KFKOmhp1ev2H24X3LQVsqCOXK+1HqLxdPwA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00055

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}