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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ad6bbf37f20cc9ce726f928c28238b319f117bfac5e55795bd36c513558d6d50' 
  AND token = 'qOUJWVS/SUqwAt6/1nkM0dNsnC1eetY4GoE4vcBu5Q4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}