SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3add10f1a6f9a67698516f74fdaf34fcdf2161cd8ad6e60533b4027be1f15f01' 
  AND token = 'dRuI0CsGFqYn3mBspRbIEOTrZVKqkp524z/QqtpdI+Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}