SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '06ed5e43aa8df0040fbab2f056b0cae3fd674d79574ca22cfa6390c6a72a7510' 
  AND token = 'eEzDFDfeYEPZHq2kqaRZLhmEo0Yp23RcfMPCX06iJFU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}