SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c4cf75e3a7461dc76eafaf8f73bee1b4980e5f8320a94df40ce360acc5e626e4' 
  AND token = 'YYTloxUdGIYpMZOa3qfQgblDdB0Zt3LgNP0QkKHeWos=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00045

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}