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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1cf9049db30d1cc480ba13671f5b6e705b1f6e23346a30305c5f14a6d8ed0b67' 
  AND token = 'IMxqwkjfc8IPqbq3CLqocjf2Wo1TF8DdycrCpWu6Vr0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}