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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f126a50a1299aeee9a4ef791bda739269269f6cfd01abcca3e5b6d5f42a38c01' 
  AND token = 'K4NbdKD+4T3ezmSNjPwNYGjTckZVjeSw3a/M3lIqd7c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}