SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '687de49394f1df900e5b68b8dde1738e30550ff52b3d348abaff4ced6f6e90cb' 
  AND token = 'WqmZp0vnzrZ3F+Cgce70r861mlDZmjpBd3osZco2JVM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}