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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cc57e0fb9e388f0e62e539e215ae7c51deb9d07e0e32ffabfba95bcc65a5f426' 
  AND token = 'DMW2FzSZTpJlxlJB9p+psvRVsTt+oAq9rj8Ys1kuFSA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00013

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}