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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b2b46601ca64bb851386e7387127afdd5d2e3ee6e73c9c1f6d3f2adedf3b46ee' 
  AND token = 'tvMpcx7V+xsKPFAhu8hGkcH90rYsNSY2DgE/lljaNFk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}