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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5038df89eead665895550f9360f5fbcb23c1e0b6df154dbd89dc2c526c2ad930' 
  AND token = 'bzibz4c7NPp+uHnDSnxC7dO4Pg3jYJO6MY+VZwgI1Xk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}