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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'bbd48849cc28e9fd31823799c937898d44615e0155205f37de1d4b3e9118973c' 
  AND token = 'ApMvOdz0vc+2I9VfuBl7A5SmrW0yq3EDdbqRZSuBe/0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}