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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'acd6f1da28482c358b79908550d51377a3303c93c99cd7e4f5f932d765bc9e03' 
  AND token = 'LGb0ZG36PQJ9lH1z4rFN7I/OGUXtUN7vQ3kTr9KHj6o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}