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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6be0e5f8336d8aa60bdf61fe01f6502c1b2c61cd2015012d9da020ef8c0e6719' 
  AND token = 'jbyxaf5M4/+ir4wf5K4tAM1LfepfwBQ2Xy43Geh/r5w=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00052

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}