SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '79edd78c877aa4de9f444025dd96b0d4223b52f056e8095115a2ddb43047ed11' 
  AND token = 'sT6RN3ADjPSctFnSQrruVY66caXYuGP2nuZRTEvO2S4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}