SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '389906f25fc9838cbb3e733db3438971dd8bea9b884d4ec31779f4dee7aad8b3' 
  AND token = 'zwyYGEe/90WeGrF5z016WId3RK98RIVIbg0xqXz/e8g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}