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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9a09bd433751438d0a25d7b75a26e106cfb297e2d59dedb55450b4c4a8fd7efe' 
  AND token = 'SqO/iJY/gblhq43fU9LVsFYhFG7rqddh0iSUOeyztaQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}